Active Clinical Trials

Clinical trials are at the heart of our work to bring innovative medicines to people with a particular disease or condition. Learn more about the active studies conducted by Novartis including opportunities to get involved.

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Study title Condition Phase Location

A Study to Investigate the Pharmacokinetics and Safety of Remibrutinib in Participants With Severe Renal Impairment Compared to Matched Healthy Participants.

Autoimmune and Chronic Inflammatory Diseases Phase1 United States

Dose Optimization and Expansion Study of DFV890 in Adult Patients With Myeloid Diseases

Myeloid Diseases Phase1 France
Germany
Hong Kong
Italy
Singapore
Spain
United Kingdom
United States
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Study of Efficacy and Safety of LNP023 in Participants With Active Lupus Nephritis Class III-IV, +/- V

Lupus Nephritis Phase2 Argentina
Brazil
China
Colombia
France
Germany
Hong Kong
Hungary
India
Israel
Malaysia
Mexico
Philippines
Portugal
Puerto Rico
Singapore
Spain
Turkey (Türkiye)
United Kingdom
United States
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Registry of Patients With a Diagnosis of Spinal Muscular Atrophy (SMA)

Spinal Muscular Atrophy (SMA) Greece
Ireland
Israel
Poland
Portugal
Romania
Russia
South Korea
Taiwan
United States
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Phase I/II Study of [225Ac]Ac-PSMA-R2 in PSMA-positive Prostate Cancer, With/Without Prior 177Lu-PSMA RLT

Prostate Cancer Phase1, Phase2 Australia
Canada
France
United States
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Safety and Efficacy Study of Fingolimod in Taiwanese Adults (≥ 20years) With Relapsing Remitting Multiple Sclerosis

Multiple Sclerosis Phase4 Taiwan

Long-term Efficacy, Safety and Tolerability of Iptacopan in C3G or IC-MPGN

C3 Glomerulopathy, Immune-complex-membranoproliferative Glomerulonephritis Phase3 Argentina
Brazil
China
France
Germany
Greece
Israel
Italy
Japan
Netherlands
Spain
Switzerland
Turkey (Türkiye)
United Kingdom
United States
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A Study of 177Lu-FAP-2286 in Advanced Solid Tumors

Solid Tumor Phase1, Phase2 Australia
Canada
United States

Evaluate Long-term Safety, Tolerability and Efficacy of Iptacopan in Study Participants With aHUS

Atypical Hemolytic Uremic Syndrome Phase3 Brazil
China
Czechia
India
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Study of Efficacy and Safety of Ruxolitinib in Chinese Participants With Corticosteroid-refractory Chronic Graft vs. Host Disease

Graft vs. Host Disease, Chronic Graft vs. Host Disease, Corticosteroid-refractory Chronic Graft vs. Host Disease Phase4 China