Active Clinical Trials

Clinical trials are at the heart of our work to bring innovative medicines to people with a particular disease or condition. Learn more about the active studies conducted by Novartis including opportunities to get involved.

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Study title Condition Phase Location

A Phase II Trial to Evaluate the Clinical Efficacy, Safety and Tolerability of MAS825 in Pediatric and Adult Participants With Still's Disease

Still´s Disease Phase2 Canada
United States

A Phase I/II, Dose Finding and Optimization Study of [177Lu]Lu-NeoB in Combination With Capecitabine in Patients With GRPR+, ER+, HER2- Metastatic Breast Cancer After Progression on Previous Endocrine Therapy in Combination With a CDK4/6 Inhibitor.

Breast Cancer Phase1, Phase2 Australia
Canada
China
France
Germany
Italy
Netherlands
Portugal
Singapore
South Korea
Spain
United Kingdom
United States
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Open-label, Multi-center, Phase I/II Study to Assess Safety, Disease Progression and Cellular Kinetics Following YTB323 Administration in Participants With Non-active Progressive Multiple Sclerosis (PMS)

Progressive Multiple Sclerosis Phase1, Phase2 Australia
Canada
France
Germany
Italy
Spain
Switzerland
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A Long-term Safety Study in Brazilian Patients With a Diagnosis of Spinal Muscular Atrophy Treated With Zolgensma

Spinal Muscular Atrophies Brazil

24 Weeks Double-blind Randomized Placebo-controlled Trial to Evaluate Efficacy, PK, Safety of LOU064 in Adolescents (12 - <18) With CSU and Inadequate Response to H1-antihistamine Followed by Optional 3 Years Open-label Extension and an Optional 3 Years Safety Long-term Treatment-free Follow-up

Chronic Spontaneous Urticaria Phase3 Argentina
Canada
China
Germany
Hong Kong
Italy
Japan
Malaysia
Netherlands
Poland
Singapore
South Africa
Spain
Thailand
Turkey (Türkiye)
United Kingdom
United States
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Study of 177Lu-PSMA-617 In Metastatic Castrate-Resistant Prostate Cancer in Japan

Prostate Cancer Phase2 Japan

Phase 2 Study Evaluating Rapcabtagene Autoleucel in Participants With Diffuse Cutaneous Systemic Sclerosis

Scleroderma, Diffuse Phase2 Australia
Austria
Czechia
Denmark
France
Germany
Hungary
Israel
Italy
Japan
Netherlands
Singapore
South Korea
Spain
Switzerland
Taiwan
United States
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Assessing Short-term Treatment Satisfaction and Quality of Life in Patients With Hidradenitis Suppurativa Initiated on Secukinumab.

Hidradenitis Suppurativa United Arab Emirates

Study of Out of Specification for Tisagenlecleucel

B-cell Acute Lymphoblastic Leukemia, Diffuse Large B-cell Lymphoma Phase3 Japan

Open-label Study Comparing AAA817 Versus Standard of Care in the Treatment of Previously Treated PSMA-positive mCRPC Adults Who Have Disease Progressed on or After [177Lu]Lu-PSMA Targeted Therapy

Prostate Cancer Phase2, Phase3 Australia
Brazil
China
Israel
Japan
Singapore
South Korea
Taiwan
United States
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